Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common ...
Brain tumors do not just invade healthy tissue. They also physically squeeze it, and that mechanical compression may be enough to trigger neuron death in the surrounding brain. Two peer-reviewed ...
(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...
New research shows that physical pressure from brain tumors or injuries triggers a "self-destruction" program in neurons, leading to irreversible brain damage.
Researchers at St. Jude Children's Research Hospital have uncovered a new pathway for mitochondrial cell death that involves the protein BCL-2 ovarian killer, otherwise known as BOK. The discovery, ...
A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate ...
Immunometabolism has emerged as a central hub linking infection, inflammation, cell death, and cancer. The metabolic state of cells profoundly shapes their ...
In cells, CENP-A binds to histone H4 and HJURP before it is incorporated into the centromere. The previous model proposed that HJURP recognizes Mis18C and CENP-A is incorporated into the centromere ...