Edward's Syndrome (Trisomy 18) Trisomy 18, also known as Edward's syndrome, is a rare and very serious genetic condition caused by the presence of an extra copy of chromosome 18. Instead of the usual two copies, a person with Trisomy 18 has three copies. This extra genetic material disrupts normal development, leading to severe intellectual disability and life-threatening medical problems. It is the second most common autosomal trisomy after Down syndrome (Trisomy 21), but it is much more severe

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